منابع مشابه
Intrathecal drug spread.
Correspondence Intrathecal drug spread Editor—I read with interest the review by Hocking and Wildsmith 1 on intrathecal drug spread. I feel they omitted to mention an important aspect of drug spread that could have a bearing for all blocks. They quite rightly stated that vasoconstrictors added to intrathe-cal local anaesthetic could prolong the duration of a block, although not affect the heigh...
متن کاملInteraction between baricity (glucose concentration) and other factors influencing intrathecal drug spread.
The effects of intrathecal injection of 0.5% bupivacaine in solutions containing various concentrations of glucose have been studied in four groups of 20 patients. When solutions containing 0.8% glucose were injected at the L3-4 interspace the median maximum extent of block was higher, and the range of blocks wider, with the 8% solutions. All patients receiving 0.8% glucose had blocks between t...
متن کاملEffect of dextrose concentration on the intrathecal spread of amethocaine.
Effects of solutions of 0.5% amethocaine, containing different concentrations of dextrose (0%, 1.25%, 2.5% and 5%) were studied after intrathecal injection. The cephalad extent of block was greater with all three dextrose-containing solutions (T6), compared with the isobaric solution which contained no dextrose (T11). The variability of maximum level of block within each group was similar (seve...
متن کاملCurrent perspectives on intrathecal drug delivery
Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expert panel consensus guidelines have provided care paths in the treatment of noc...
متن کاملFluid Mechanics of Intrathecal Drug Delivery
The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a larger dose continuously injected over a longer period. The subarachnoid space is modeled as an annular gap of constant or slowly varying cr...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1998
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03012016